Holistic Integrative Oncology（HIO，eISSN:2731-4529; CN12-1481/R73）是由中国抗癌协会与Springer Nature出版集团于2021年强强联合打造的一本英文大刊，主编为中国抗癌协会理事长樊代明院士。HIO入选了2022年中国科技期刊卓越行动计划高起点新刊项目，是面向全球开放的自由获取同行评议期刊，设有CACA指南、专家述评、研究综述和原创论著等栏目。肿瘤基因诊断专题文章已正式上线，敬请各位读者阅读、引用与分享！

本专题目录

01 CACA Technical guidelines for holistic integrative management of cancer —— genetic testing

文章类型：Guideline

引用格式：CACA –Committee of Cancer Genetic Diagnosis., Wei, B., Xing, J. et al. CACA Technical guidelines for holistic integrative management of cancer —— genetic testing. Holist Integ Oncol 4, 14 (2025). https://doi.org/10.1007/s44178-025-00149-5

文章链接：https://link.springer.com/article/10.1007/s44178-025-00149-5

02 Pathological mechanisms and advances in neoadjuvant PD-1 blockade combined with chemotherapy for head and neck cancer

文章类型：Commentary

引用格式：Hou, Yj., Yang, Xx. & Meng, Hx. Pathological mechanisms and advances in neoadjuvant PD-1 blockade combined with chemotherapy for head and neck cancer. Holist Integ Oncol 3, 63 (2024). https://doi.org/10.1007/s44178-024-00140-6

文章链接：https://link.springer.com/article/10.1007/s44178-024-00140-6

03 Role in development or treatment of LEF1-AS1 in tumors of the digestive system

文章类型：Review

引用格式：Ma, H., Li, L., Jiang, C. et al. Role in development or treatment of LEF1-AS1 in tumors of the digestive system. Holist Integ Oncol 4, 13 (2025). https://doi.org/10.1007/s44178-025-00150-y

文章链接：https://link.springer.com/article/10.1007/s44178-025-00150-y

04 Effectiveness of auricular acupoint therapy on chemotherapy-induced gastrointestinal reaction in breast cancer patients: a systematic review and meta-analysis

文章类型：Review

引用格式：Chen, K., Zhang, N. & Ye, T. Effectiveness of auricular acupoint therapy on chemotherapy-induced gastrointestinal reaction in breast cancer patients: a systematic review and meta-analysis. Holist Integ Oncol 3, 67 (2024). https://doi.org/10.1007/s44178-024-00147-z

文章链接：https://link.springer.com/article/10.1007/s44178-024-00147-z

05 Combining immunogenic cell death and cuproptosis to construct a prognostic signature and predict the immune status and treatment efficacy for hepatocellular carcinoma

文章类型：Original Research

引用格式：Feng, X., Li, X. & Zhang, X. Combining immunogenic cell death and cuproptosis to construct a prognostic signature and predict the immune status and treatment efficacy for hepatocellular carcinoma. Holist Integ Oncol 3, 65 (2024). https://doi.org/10.1007/s44178-024-00143-3

文章链接：https://link.springer.com/article/10.1007/s44178-024-00143-3

06 Profiling of driver mutations in lung adenocarcinoma patients identifies rare compound EGFR mutations sensitive to second-generation EGFR-TKIs

文章类型：Original Research

引用格式：Li, J., Zhang, C., Guan, Y. et al. Profiling of driver mutations in lung adenocarcinoma patients identifies rare compound EGFR mutations sensitive to second-generation EGFR-TKIs. Holist Integ Oncol 3, 64 (2024). https://doi.org/10.1007/s44178-024-00139-z

文章链接：https://link.springer.com/article/10.1007/s44178-024-00139-z

07 Expression and correlation of Surfeit 4 gene in esophageal squamous cell carcinoma

文章类型：Original Research

引用格式：Liu, Jx., Lu, T., Xia, Y. et al. Expression and correlation of Surfeit 4 gene in esophageal squamous cell carcinoma. Holist Integ Oncol 3, 66 (2024). https://doi.org/10.1007/s44178-024-00141-5

文章链接：https://link.springer.com/article/10.1007/s44178-024-00141-5

08 Extrachromosomal circular DNA: enlightenment to widespread clinical application

文章类型：Short Communication

引用格式：Wang, S., Li, H., Zhang, Y. et al. Extrachromosomal circular DNA: enlightenment
to widespread clinical application. Holist Integ Oncol 4, 8 (2025). https://doi.org/10.1007/s44178-025-00151-x

文章链接：https://link.springer.com/article/10.1007/s44178-025-00151-x

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